Givaudan Active Beauty launches Illuminyl™ 388, a highly potent skin brightening prebiotic paving the way for inclusivity.

Illuminyl™ 388 by Givaudan Active Beauty is a biotech-enhanced molecule designed through cell-free glycosylation to address the challenges of skin pigmentation for all skin types. Crafted through a unique biocatalysis process from EpiGalloCatechin Gallate, green tea’s most iconic antioxidant, this ingenious brightening molecule delivers a holistic luminous effect.
Inclusive skincare innovation
At the heart of Illuminyl™ 388 is a commitment to inclusivity in skincare innovation. This bio-based active has been designed to simultaneously target multiple skin pigmentation pathways and is reinforced by additional prebiotic activity to meet the needs of diverse skin types from Africa, Asia, India, and Europe.
Givaudan Active Beauty undertook in-depth and global clinical studies, engaging over 200 volunteers comprised of 4 diverse skin tones (African, Asian, Indian, and Caucasian). The results showed that Illuminyl™ 388 can:
- Improve skin radiance in just two weeks
- Enhance skin tone & luminosity in just two weeks
- Reduce pigmentation spots in just one month
- Enhance skin tone homogeneity, even tackling stubborn age spots.
Illuminyl™ 388 has a unique bioavailability with an in-depth skin penetration profile. Its sugar moiety enables its absorption via cellular glucose receptors, while conferring on the molecule a prebiotic activity which stimulates the in-situ release of a niacin-derivative by the skin microflora.
Brightening and balanced skin microbiota
Daniel Auriol, scientific director biotechnology – Active Beauty, comments: “Clinical studies conducted on four different skin types underline the universal efficacy of this skin illuminating active. Givaudan Active Beauty continues to push the boundaries of innovation with Illuminyl™ 388. We are not only targeting all the major pigmentation pathways, but also triggering the skin microbiota to produce whitening postbiotics. Whether improving skin radiance and luminosity, promoting even skin tone, or reducing pigmentation spots, Illuminyl™ 388 outperforms traditional benchmarks such as vitamin C. It is a testament to our commitment to redefining beauty standards and empowering individuals worldwide.”
Achieving a B-Biome™ Score of ’B’, this brightening active works in synergy with the microbiome to preserve the general balance of the skin’s microbiota.1
To learn more about Active Beauty’s new ingredient and its marketing concept, S3D® Lumière Noire, Givaudan invites you to visit their stand (1C62) at in-cosmetics Global, taking place in Paris, France. You can also visit the supplier’s digital platform dedicated to cosmetic ingredients.
Givaudan Active Beauty is represented by The Care Co. in South Africa.
Reference:
- The first scientifically proven, 100% transparent and microbiome-friendly label for cosmetic ingredients.









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